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Br J Ophthalmol 83:1159-1163 doi:10.1136/bjo.83.10.1159
  • Original Article
    • Clinical science

Grading nuclear cataract: reproducibility and validity of a new method

Table 2

Mean difference between repeat measurements, repeatibility coefficients, and intraclass correlation coefficients for each method of cataract grading. (Calculated on 113 eyes, each measured twice)

Laser slit lamp LOCS III score
pixel intensity Nuclear colour Nuclear opalescence
Mean difference (session 2–session 1) (95% CI)  0.40 (−0.24–1.04)  0.06 (−0.01–0.13)  0.06 (−0.01–0.14)
Intraclass correlation (%) (95% CI)
Healthy subjects 38.6 (12.9–59.2) 82.3 (71.1–89.4) 76.1 (62.3–85.4)
Cataract subjects 94.7 (91.2–96.9) 94.1 (90.2–96.4) 93.5 (89.4–96.1)
All subjects 95.0 (92.9–96.5) 96.7 (95.3–97.8) 97.0 (95.6–97.9)

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