Table 5
Analysis of antibody staining in grafted corneas
| Patient group | Grade of antibody staining | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| CD3 | CD4 | CD8 | CD14 | CD68 | CD25 | HLA-DR | HLA-DP | CD1a/MHC class II | |
| Group 1 (n=10) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Group 2 (n=15) | 0.67 (1.17) | 0.37 (0.61) | 0.87 (0.83) | 2.14 (1.70) | 2 (1.24) | 0.47 (0.51) | 2.8 (1.33) | 2.27 (1.33) | 1.34 (1.16) |
| Group 3 (n=5) | 2 (0.63) | 0.80 (0.74) | 1.8 (0.74) | 3 (0.89) | 3.8 (0.89) | 0.8 (0.4) | 3.4 (0.8) | 3.2 (0.74) | 1 (1.09) |
| p Value | 0.005 | 0.128 | 0.034 | 0.101 | 0.05 | 0.101 | 0.198 | 0.046 | 0.309 |
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↵Grades 0–4 based on actual cell counts in tissue sections (see Methods). Scores represent mean grade (SD) with n = number of samples as indicated.
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↵Significance of differences between group 2 (clinically no inflammation) and group 3 (clinically inflamed) patients. Statistics were not applied to data combining groups 1 and 2 and groups 1 and 3 since no inflammatory cells were observed in the dystrophic corneas and they are clearly different (score zero).
