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Br J Ophthalmol 83:162-167 doi:10.1136/bjo.83.2.162
  • Original Article
    • Clinical science

Effect of isosorbide mononitrate on the human optic nerve and choroidal circulations

Table 3

Choroidal data (mean (SEM))

Percentage change from baseline Placebo ISMO p Value
placebo v ISMO
Blood velocity (Ch vel):
1 hour (n=12) +1.0 (6.1) −3.0 (3.4) 0.562
 3 hours (n=6) +2.3 (5.5) −2.5 (2.0) 0.382
Blood volume (Ch vol):
1 hour (n=12) +4.3 (12.4) −0.7 (7.5) 0.972
 3 hours (n=6) −8.3 (7.7) −1.1 (5.0) 0.586
Blood flow (Ch flow):
1 hour (n=12) +8.2 (11.0) −3.9 (6.7) 0.406
 3 hours (n=6) −6.4 (9.5) −3.6 (4.5) 0.828
  • Paired, two tailed Student’s ttest for the comparison between percentage changes following placebo and ISMO.

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