Table 3
Sensitivity and specificity of morphometric optic disc variables, measured by confocal laser scanning tomography, in the differentiation of normal eyes, eyes with preperimetric glaucoma, and eyes with perimetric glaucoma. p Values, calculated for the significance of differences to the normal group (ranked Mann–Whitney U test). All variables of the perimetric glaucoma group were significantly reduced (p<0.001)
| HRT variable | Region | Mann–Whitney test (p value) preperimetric OAG | Sensitivity (%) (specificity 95%) preperimetric OAG | Sensitivity (%) (specificity 95%) perimetric OAG |
|---|---|---|---|---|
| Rim area | all | 0.02 | 11.8 | 65.6 |
| superior | 0.001 | 24.8 | 72.1 | |
| inferior | ns | 8.8 | 57.4 | |
| Rim volume | all | 0.0002 | 19.6 | 67.2 |
| superior | 0.0001 | 25.5 | 73.8 | |
| inferior | 0.002 | 11.8 | 60.7 | |
| RNF thickness | all | 0.004 | 19.6 | 54.1 |
| superior | 0.007 | 18.6 | 50.8 | |
| inferior | 0.04 | 26.5 | 60.7 | |
| Cup area | all | 0.04 | 13.7 | 57.4 |
| superior | 0.02 | 13.7 | 60.7 | |
| inferior | ns | 5.9 | 36.1 | |
| Cup volume | all | ns | 15.7 | 49.2 |
| superior | 0.02 | 23.5 | 60.7 | |
| inferior | ns | 13.7 | 49.2 | |
| Cup shape measure | all | ns | 9.8 | 42.6 |
| superior | 0.004 | 7.8 | 36.1 | |
| inferior | ns | 2.9 | 26.2 | |
| Multivariate analysis | <0.0001 | 42.2 | 83.6 |
