Ophthalmic findings in patients with myotonic dystrophy
| Patients | Age/ duration/ sex | Visus pre/post operation | Lens opacity | Retinal changes | ERG | Corneal CD (cells/mm2) |
Lens CD (cells/ mm2) |
Myotonia/ heart abnormality |
|---|---|---|---|---|---|---|---|---|
| 1 H-II-2 | 59/16/M | LS/0.6 | MCIO | + | OPsA | 3676 | 3802 | +/+ |
| HM/0.7 | MCIO | + | OPsA | 3095 | 3144 | +/+ | ||
| 2 T-II-4 | 58/21/F | 0.3/0.9 | MCIO | + | OPsA | 2865 | 2506 | +/+ |
| 0.4/1.0 | MCIO | + | OPsA | 3044 | 2849 | +/+ | ||
| 3 O-III-1 | 33/2/M | 0.06/1.0 | PSCO | − | OPsA | 3620 | 1326 | +/+ |
| 0.03/1.0 | PSCO | − | OPsA | 2868 | 1543 | +/+ |
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↵Age/duration/sex indicate the age and sex of the patients and duration of the disease; visus pre/post operation: best corrected visual acuity before and after operation; ERG=electroretinogram; corneal CD= corneal endothelial cell density; lens CD= lens epithelial cell density; myotonia and heart abnormality= patients who showed muscle weakness or myotonia in any other place in the body or who had heart abnormalities detected by electrocardiogram or cardioechography;
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LS:=light sensitivity; HM= hand movements; MCIO:=multicoloured iridescent opacity; PSCO= posterior subcapsular opacity; OPsA=attenuated oscillatory potentials; the lens CD in patients with MD (average 2274 cells/mm2) was statistically significant, compared with controls with senile cataracts (average 4627 cells/mm2) (p=0.004).
