Table 1
Correlations between demographic, thyroid, and orbital variables, and serum antibodies against the flavoprotein (Fp) subunit of succinate dehydrogenase in patients with thyroid associated orbitopathy
| (+) anti-Fp antibodies (n=24) |
(-) anti-Fp antibodies (n=14) |
p Value | |
|---|---|---|---|
| Age (mean (SD)) | 51.0 (14.24) | 50.9 (8.44) | >0.05 |
| Sex (M/F) | 8/16 | 2/12 | >0.05** |
| Current smoking (Y/N) | 10/12 | 7/6 | >0.05** |
| Thyroid disease: | |||
| Duration (months) (mean (SD)) | 26.8 (37.15) | 29.0 (43.68) | >0.05 |
| Status: | |||
| Hyperthyroid | 12 | 9 | >0.05 |
| Euthyroid | 9 | 2 | >0.05 |
| Hypothyroid | 1 | 1 | |
| Treatment: | |||
| I131 | 11 | 7 | |
| Propylthiouracil | 3 | 1 | |
| Tapazole | 0 | 1 | |
| None | 4 | 1 | |
| Orbitopathy: | |||
| Duration (months) (mean (SD)) | 3.9 (2.03) | 3.5 (1.74) | >0.05 |
| Activity (mean (SD)) | 2.8 (0.9) | 2.5 (0.7) | >0.05 |
| Lid retraction (Y/N) | 17/7 | 9/5 | >0.05** |
| †EOM (mean (SD)) | 4.8 (2.8) | 2.5 (3.4) | <0.05 |
-
↵Student’s t test; **Fisher’s exact test. †EOM = number of involved extraocular muscles.
