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Br J Ophthalmol 83:616-621 doi:10.1136/bjo.83.5.616
  • Original Article
    • Laboratory science

Correlation of histological findings with gadolinium enhanced MRI scans during healing of a PHEMA orbital implant in rabbits

Table 1

Summary of histological and imaging findings

Time implanted (no of specimens) Histological findings Imaging findings
3 weeks to 2 months (3) Fibroblasts ++ Enhancement ++++
Blood capillaries +++ No calcium detected
Inflammation +++ Capsule +
Calcium deposits +
4 months (1) Fibroblasts +++ Enhancement +++
Blood capillaries ++ No calcium detected
Inflammation + No capsule
Calcium deposits +
6 months (2) Fibroblasts +++ Enhancement ++
Blood capillaries ++ No calcium detected
Inflammation + No capsule
Calcium deposits +
12 months (2) Fibroblasts +++ Enhancement +
Blood capillaries + Calcium deposit seen in one animal
Inflammation + No capsule
Calcium deposits ++

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