Table 3
Growth factor immunoreactivity in the outer nuclear layer following laser photocoagulation
| GFs/GF-R | CTL | Non-lasered regions | Laser treated regions | |||||
|---|---|---|---|---|---|---|---|---|
| 1 Hour–42 days | 1 Hour | 4 Days | 7 Days | 21 Days | 42 Days | |||
| bFGF | + | + | + | + | +/++ | +++ | + | |
| IGF-I | + | + | + | ++/++ + | +++ | +++ | + | |
| TGF-β | + | + | + | +++ | +++ | +++ | + | |
| PDGF-AB | - | − | − | − | −/+ | ++ | − | |
| TGF-α | − | − | − | − | +/++ | ++ | − | |
| EGF | − | − | − | − | ++ | − | − | |
| EGF-R | − | − | − | +/++ | +/++ | ++ | − | |
-
GFs=growth factors; GF-R=growth factor receptor; CTL=control non-lasered retina.
-
−=negative; +=weak immunoreactivity; ++=moderate immunoreactivity; +++=intense immunoreactivity; /indicates immunoreactivity in different burn areas varied between the limits shown.
