Table 1
Cell surface antigens against which monoclonal antibodies have been used in this study, and their specificity
| Antigen | Specificity |
|---|---|
| CK-MNF | Pancytokeratin, epithelial tissue |
| Collagen type IV | Basal membranes |
| Vimentin | Intermediate filament, solely expressed by cells of mesenchymal origin and used as a marker for such |
| CD 3 | Cell surface antigen on all T cells |
| CD 4 | Cell surface antigen expressed on T helper cells and thymocytes; important for stabilisation of the T cell receptor-MHC II interaction |
| CD 8 | Cell surface antigen expressed by cytotoxic T cells, intraepithelial lymphocytes, thymocytes, and some dendritic cells |
| CD 15 | Marker for cell activation predominantly expressed by granulocytes and, to some extent, by macrophages |
| CD 20 | Cell surface antigen found on nearly all B cells except pre-B cells and plasma cells. Represents a transmembraneous ion channel protein and plays an important role in the activation and proliferation processes of the maturing B cell |
| CD 68 | Cell surface antigen found on macrophages and monocytes |
| CD 79a | Cell surface antigen expressed early in the ontogenesis of B cells, persistent in plasma cells, but not co-expressed with CD20+ |
