Table 3
Factors thought to differentiate between necrosis and apoptosis
| Necrosis | Apoptosis |
|---|---|
| • Occurs in groups of cells | • Occurs in isolated cells |
| • Gene expression not a | • Genetically controlled |
| prerequisite | • Precise internucleosomal cleavage of |
| • Late stage random DNA | DNA |
| cleavage | • No inflammation |
| • Inflammatory response | • Phagocytosis of apoptotic bodies by |
| • Phagocytosis of debris by macrophages | tissue cells and/or macrophages |
