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Br J Ophthalmol 1999;83:987 doi:10.1136/bjo.83.8.987f
  • Letter to the Editor

Iopidine allergy causing lower eyelid ectropion progressing to cicatricial entropion

  1. MICHELLE T BRITT,
  2. MICHAEL A BURNSTINE
  1. Department of Ophthalmology and Doheny Eye Institute, University of Southern California School of Medicine, Los Angeles, California
  1. Michael A Burnstine, MD, Doheny Eye Institute, University of Southern California, 1450 San Pablo Street, Los Angeles, CA 90033, USA.
  • Accepted 16 March 1999

Editor,—Apraclonidine hydrochloride 1% (Iopidine) is a selective α2-adrenergic agonist used to treat glaucoma or to protect against pressure spikes before laser treatments. Up to 48% of patients taking Iopidine for over 3 weeks develop follicular conjunctivitis.1 2 Periocular contact dermatitis was also associated with Iopidine allergy in 62% of the cases.2 We report a case of an Iopidine allergic reaction presenting with eyelid ectropion which further progressed to cicatricial entropion.

CASE REPORT

A 64 year old man was referred with a 6–8 month history of non-resolving conjunctivitis, epiphora, and resultant left lower eyelid …

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