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Letter to the Editor
Somatostatin scan positive gastrinoma ocular metastasis
  1. KEIR E LEWIS,
  2. PAUL B ROGERS
  1. Department of Clinical Oncology
  2. Department of Ocular Oncology
  3. Department of Nuclear Medicine
  4. Department of Clinical Oncology, St Bartholomew’s Hospital, West Smithfield, London EC1A 7BE
  1. JOHN HUNGERFORD
  1. Department of Clinical Oncology
  2. Department of Ocular Oncology
  3. Department of Nuclear Medicine
  4. Department of Clinical Oncology, St Bartholomew’s Hospital, West Smithfield, London EC1A 7BE
  1. KEITH E BRITTON
  1. Department of Clinical Oncology
  2. Department of Ocular Oncology
  3. Department of Nuclear Medicine
  4. Department of Clinical Oncology, St Bartholomew’s Hospital, West Smithfield, London EC1A 7BE
  1. P NICHOLAS PLOWMAN
  1. Department of Clinical Oncology
  2. Department of Ocular Oncology
  3. Department of Nuclear Medicine
  4. Department of Clinical Oncology, St Bartholomew’s Hospital, West Smithfield, London EC1A 7BE
  1. Dr Plowman.

https://doi.org/10.1136/bjo.83.9.1088h

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    Editor,—Symptomatic ocular metastases are uncommon despite the 4% prevalence in patients dying of all types of malignancy in postmortem series.1 We report a case of ocular metastasis from a gastrinoma, which was part of the Wermer’s syndrome (multiple endocrine neoplasia (MEN) type 1), diagnosed by indium labelled octreotide scanning.

    CASE REPORT

    A 57 year old man presented with a 1 week history of blurring in his peripheral vision in his right eye and severe loss of visual acuity, worse early morning. He had been diagnosed with MEN type 1, 8 years previously after two perforated jejunal ulcers (1978, 1990) led to a diagnosis of Zollinger–Ellison syndrome, and a hyperplastic parathyroid gland had been removed for hypercalcaemia (1990). His mother had MEN type 1.

    Ophthalmic examination revealed 6/12 acuity in the …

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