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Br J Ophthalmol 84:98-102 doi:10.1136/bjo.84.1.98
  • Original Article
    • Laboratory science

Effects of proton beam irradiation on uveal melanomas: a comparative study of Ki-67 expression in irradiated versus non-irradiated melanomas

Table 1

Correlations between Ki-67 score and clinicopathological findings in the overall population

Factors Correlation coefficient p Value
Mitosis 0.562 0.001
Histological LTD 0.38 0.038
Fibrosis −0.35 0.05
Mean (SD) of Ki-67 score p Value
Tumoral pigmentation 0.048
 Absence 3.1 (2.6)
 + 0.8 (0.9)
 ++ 1.5 (1.1)
 +++ 0.62 (0.6)
Vascular lesions 0.03
 Absence 1.49 (1.9)
 Hyalinised vessel wall 1.31 (1.1)
 Thrombosis 0.09 (0.15)
Treatment 0.013
 Control group 1.7 (1.7)
 Proton beam 0.7 (1)
Cause of enucleation 0.005
 Neovascular glaucoma 0.68 (1.1)
 Tumoral evolution 1.61 (1.6)
  • LTD = largest tumour diameter.

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