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Br J Ophthalmol 84:1091-1096 doi:10.1136/bjo.84.10.1091
  • Original Article
    • Clinical science

Matrix metalloproteinases and their natural inhibitors in fibrovascular membranes of proliferative diabetic retinopathy

Table 2

Comparison between retinal membranes of PDR and PVR and normal retina in the expression of MMPs and TIMPs

MMP-1
(active + latent ) 		MMP-2
(latent) 		MMP-3
(active + latent) 		MMP-9
(active + latent) 		TIMP-1 TIMP-2 TIMP-3
PDR 66% 66% 62% 66% 71% 62% 66%
PVR 86% 81% 52% 48% 43% 33% 75%
Normal retina 100% 0% 0% 0% 0% 100% 0%

  • The figures represent the percentage of samples staining for each antibody in the different groups.

  • ↵p= 0.036 v PVR.

  • ↵Staining of the inner and outer nuclear cell layers and plexiform layers.

  • ↵Staining of the inner and outer nuclear cell layers only.

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