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Br J Ophthalmol 84:1275-1281 doi:10.1136/bjo.84.11.1275
  • Original Article
    • Clinical science

Postmortem histological survey of the ocular lesions in a British population of AIDS patients

Table 4

Histologically proved systemic infections and neoplasms (%) and concomitant ocular involvement in our series compared to two other studies

Pathology This study (73 patients) Pepose (35 patients) De Girolami (25 patients)
S S+E E S S+E E S S+E E
P carinii 18 (24.6) 26 (74) 18 (72)
CMV 42 (57.5) 15 (20.5) 6 (8.2) 25 (71.4) 12 (34.2) 9 (36) 5 (20) 3 (12)
Cryptococcus 5 (6.8) 4 (5.4) 5 (14.2) 2 (5.7) 2 (8)
T gondii 1 (1.3) 1 (2.8) 12 (48) 1 (4)
Mycobacteria 19 (26)3 4 5 12 (34.2) 2 (5.7) 3 (12)
HSV 2 (2.7) 11 (31.4) 1 (2.8) nr
VZV 4 (11.4)
Candida spp 23 (31.5) 14 (40) nr _
Aspergillus 2 (2.7) 2 (5.7)
Histoplasma 1 (1.3) 1 (1.3)
Bacteria 32 (43.8) 1 (1.3) 5 (14.2) 2 (8)
Nocardia 1 (2.8)
Lymphoma 10 (13.6) 1 (2.8) 2 (8) 1 (4)
Kaposi's sarcoma9 25 (34.2) —10 nr 3 (8.5)11 11 (44)
  • S = systemic, S+E = systemic+eye, E = eye only, nr = not reported,

  • including cerebral CMV,

  • cerebral only,

  • M avium intracellulare,

  • M kansasii,

  • M tuberculosis,

  • six cerebral and two systemic non-Hodgkin's lymphoma (NHL) + two Hodgkin's lymphoma (HL),

  • one cerebral NHL,

  • two cerebral and one systemic NHL,9cutaneous and visceral,

  • 10two cutaneous involvement of eyelids,

  • 11conjunctival.

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