Editor,—Intraocular manifestations of leukaemia are not uncommon and may be related to manifestations of the disease itself or to its complications including those of treatment. There may be direct infiltration by neoplastic cells of ocular tissue, including optic nerve, choroid, retina, iris, ciliary body, signs in the retina of associated haematological abnormalities such as anaemia, thrombocytopenia or hyperviscosity states, or retinal destruction by opportunistic infections such as that caused by herpetic viruses. In addition, occlusive retinal microvasculopathy has been reported in patients with acute leukaemia, with radiation considered to be a contributing factor in some cases.1 2