Clinical and microbiological features from 23 patients with post-trabeculectomy endophthalmitis
| Glaucoma type | Time interval | Date of presentation | Antiproliferative used | Preop IOP (mm Hg) | Preop medications | IOP at last follow up (mm Hg) | Medications at last follow up | Organism isolated | Decrease in acuity (Snellen lines) | Acuity at last follow up |
|---|---|---|---|---|---|---|---|---|---|---|
| POAG | 6 years | 1999 | 5-Fluorouracil | 27 | 1 | 14 | 1 | Moraxella | 0 | Sn 6/9 |
| POAG | 14 years | 1999 | None | 24 | 2 | 22 | 3 | 2 | Sn 6/18 | |
| POAG | 4 years | 1999º | 5-Fluorouracil | 28 | 3 | 9 | 1 | PL | ||
| POAG | 6 years | 1999 | None | 35 | 4 | 10 | 1 | Sn 6/12 | ||
| POAG | 1 month | 1998 | Mitomycin (0.2) | 24 | 3 | 10 | S viridans | 6 | CF | |
| POAG | 4 months | 1998º | 5-Fluorouracil | 25 | 12 | 4 | Sn 6/24 | |||
| Congenital | 3 years | 1998 | Mitomycin (0.4) | 33 | 2 | 10 | Gram −ve bacillus | 3 | CF | |
| AACG | 7 months | 1998 | 5-Fluorouracil | 22 | 3 | 12 | 3 | Sn 6/36 | ||
| POAG | 15 months | 1998º | 5 Fluorouracil | 26 | 1 | 4 | S pneumoniae | 5 | HM | |
| POAG | 1 month | 1998º | Mitomycin (0.1) | 18 | 1 | 16 | 1 | S p[neumoniae | 9 | PL |
| NTG | 6 months | 1998 | Mitomycin (0.1) | 16 | 12 | 3 | Sn 6/24 | |||
| POAG | 1 month | 1997 | 5-Fluorouracil | 25 | 3 | 21 | 3 | Gram −ve bacillus | 0 | Sn 6/24 |
| POAG | 3 months | 1997 | 5-Fluorouracil | 24 | 2 | 12 | 0 | Sn 6/9 | ||
| POAG | 1 month | 1997 | Mitomycin (0.2) | 22 | 2 | 21 | 2 | 1 | Sn 6/12 | |
| POAG | 4 years | 1997 | Mitomycin (0.2) | 22 | 3 | 3 | 0 | HM | ||
| Congenital | 9 years | 1997 | β radiation | 30 | 20 | 1 | H influenzae | 1 | HM | |
| Traumatic | 15 years | 1996 | None (bleb revision) | 36 | 13 | 0 | Sn 6/9 | |||
| POAG | 1 month | 1996º | 5-Fluorouracil | 26 | 2 | 18 | 2 | S aureus | 0 | Sn 6/9 |
| POAG | 2 years | 1996 | Mitomycin (0.4) | 24 | 3 | 10 | α hamolytic streptococcus | 8 | PL | |
| Congenital | 4 months | 1995 | Mitomycin (0.4) | 34 | 16 | 4 | 1 | CF | ||
| Congenital | 4 years | 1995º | Mitomycin (0.4) | 46 | 2 | 30 | 3 | S albus | 1 | PL |
| POAG | 1 month | 1994 | 5-Fluorouracil | 26 | 2 | 18 | 2 | 0 | Sn 6/9 | |
| Congenital | 6 years | 1993 | β radiation | 28 | 1 | Phthisis | 2 | NPL |
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POAG = primary open angle glaucoma; Congenital = congenital glaucoma; AACG = acute angle closure glaucoma; NTG = normal tension glaucoma; Time interval = interval between filtration surgery and episode of post-trabeculectomy endophthalmitis in whole months or years; 1999 refers to the first 6 months of 1999; β radiation applied at a dosage of 750 cGy; Preoperative IOP = IOP before filtering surgery;
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↵no vitreous tap performed (all other cases treated with intravitreal vancomycin (2 mg) and amikacin (0.4 mg);
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↵demonstrated with light microscopy, no growth on culture media;
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↵ultrasound confirmation of vitreous involvement;
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↵denotes bleb needled postoperatively; ºdenotes previous episode of blebitis;
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↵denotes bleb leak. All antiproliferative agents were applied for 5 minutes and the dose of mitomycin C is shown in parentheses. No patients were prescribed topical antibiotics for more than 3 weeks following trabeculectomy surgery.
