Article Text
Letter to the Editor
Sustained remission of CMV retinitis in HIV-2 disease
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Editor,—The only established risk factor for the development and progression of cytomegalovirus retinitis (CMVR) in individuals with HIV disease is a low CD4+ T lymphocyte count. The initiation of highly active antiretroviral treatment (HAART) has brought a significant change in the clinical outcome of CMV retinitis1 with studies reporting longer times to CMV relapse. These findings correlate with increased CD4+ T lymphocyte counts and reduced HIV viral loads.
We report the case of an HIV-2 positive patient who showed no reactivation of CMV retinitis for 25 months despite a low CD4+ T lymphocyte count and a lack of response to HAART treatment. The role of HIV-2 seropositivity in our …