Table 1

Clinical details and tumour size, location, cell type, growth fraction, telomerase activity, and hTR expression of the uveal melanomas examined

Case	Age	Location	Size (mm)	Cell type	Degree of pigmentation	Outcome	MIB 1 (%)	ISH hTR	TRAP assay (rTA units)
1	61	anterior equator	12×10×3	mixed, spindle epithelioid	strong	awm	10	++	40
2	71	orbit	28×27×22	mixed, spindle epithelioid (original tumour, spindle)	moderate	d	10	+++	35
3	62	anterior	16×14×11	mixed, spindle epithelioid	moderate strong	awm	20	++	20
4	73	anterior equator	12×12×11	mixed, spindle epithelioid	moderate	awm	15	++	30
5	65	equator	12×11×11	mixed, spindle epithelioid	mild	d	15	++	35
6	71	equator	12×9×12	mixed, spindle epithelioid	mild	a	5	++	35
7	43	equator	14×12×11	mixed, spindle epithelioid	moderate	d	5	++	35
8	50	anterior	9×8×2	mixed, spindle epithelioid	mild	a	5	+	25
9	31	anterior	18×12×7	mixed, spindle epithelioid	moderate	a	10	++
10	87	anterior posterior	23×17×12	mixed, spindle epithelioid	moderate	a	10	++
11	55	anterior	18×15×11	mixed, spindle epithelioid	moderate	a	10	++
12	33	equator	17×10×10	spindle	mild	d	10	+
13	81	posterior	12×10×5	spindle	mild	awm	5	++
14	54	posterior	15×10×15	mixed, spindle epithelioid	mild	d	10	++

↵a = alive without metastases; awm = alive with metastases; d = dead.
↵Intensity of telomerase signal in hTR: + = mild, ++ = moderate, +++ = strong, ++++ = intense.

Telomerase expression in uveal melanoma

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