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Br J Ophthalmol 84:378-384 doi:10.1136/bjo.84.4.378
  • Original Article
    • Clinical science

Fluoroquinolone and fortified antibiotics for treating bacterial corneal ulcers

Table 8

Characteristics of patients with complications

Case No, age, sex Visual acuity Organisms Resistance Systemic disease Immunosuppression Prestudy pathology Rx modification Complication/ outcome (day)
Admission Follow up
Combined fortified group (9 patients)
1, 76, F PL No organism Diabetic Corneal oedema Enucleation (8)
2, 80, F HM PL Moraxella Rh arthritis, Corneal scar PK (4)
S epidermidis HTN Glaucoma
S pneumoniae
3, 89, M HM S epidermidis HTN Corneal scar, ectropion PED, conj flap (22)
Peptic ulcer Lagophthalmos
4, 94, F 6/60 6/60 S epidermidis Topical steroid Neutropic cornea PED, healed
Herpes zoster (past)
5, 97, M PL PL P aeruginosa HTN/Parkinson's Glaucoma Tarsorrhaphy
Planned, DNA
6, 92, F HM HM S pneumoniae HTN Topical steroid Glaucoma Topical vancomycin Tarsorrhaphy (31)
S aureus Systemic cefazolin, ciprofloxacin
7, 75, F NPL S haemolyticus Glaucoma Subconjunctival gentamicin Enucleation (3)
Systemic ciprofloxacin, penicillin
8, 76, F HM PL Moraxellasp Cefazolin Topical steroid Corneal scar Systemic ciprofloxacin, gentamicin PED, conj flap (26)
presumed HIV keratitis Topical antiviral
9, 85, F 1/36 HM Alpha haemolytic Diabetes Scar (trachoma) Systemic cefazolin PK (3)
streptococci Tobramycin
Staphcoag −ve
Fluoroquinolone group (9 patients)
10, 78, F HM Moraxella HTN/gout Evisceration (13)
Corynebacterium
11, 77, M NPL No organism HTN Corneal scar Enucleation (8)
Oedema
Glaucoma
12, 93, M PL P mirabilis Topical steroid Evisceration (8)
S epidermidis,
Staph coag −ve
13, 96, F NPL No organism Corneal scar Evisceration (2)
Glaucoma
14, 84, M 6/60 6/36 No organism Rh arthritis Systemic steroid Corneal scar Perforation
Glaucoma PK (7)
15, 82, M PL PL P acnes HTN Trauma Perforation
Staph coag −ve Glue and SBCL (6)
16, 54, M PL PL Staph Diabetes Topical steroid Vascularised Perforation
Coag −ve Corneal scar Glue and BCL (10)
17, 87, M HM HM Corynebacterium HTN Corneal scar Aciclovir Perforation
Moraxella Skin cancer Presume HSV Glue and BCL (2)
Staphcoag −ve Neurotropic cornea
Lagophthalmos
18, 84, M 6/60 6/18 Corynebacterium HTN Dry eye Aciclovir Perforation
Corneal scar
Neurotropic cornea PK (4)
Presumed HSV

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