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Br J Ophthalmol 84:499-505 doi:10.1136/bjo.84.5.499
  • Original Article
    • Clinical science

A controlled study of vigabatrin and visual abnormalities

Table 7

The probability value for each of the antiepileptic drugs (AEDs) studied being significantly associated with greater than 10% VFD using the Kruskal-Wallis one way analysis of variance when comparing the three groups: patients currently on the AED, patients previously on the AED, and patients never on the AED, after eliminating all the patients with visual pathway abnormalities

AED Kruskal-Wallis Asymmetrical significance
VGB 9.952 0.007
CBZ 2.664 0.264
PHT 0.815 0.664
CLB 2.147 0.143
GBP 1.437 0.487
TPR 0.429 0.513
PHB 3.619 0.164
VPA 3.481 0.175
DZM 0.905 0.342
LTG 0.905 0.342
  • VGB = vigabatrine, CBZ = carbamazepine, PHT = phenytoin, CLB = clobazam, GBP = gabapentin, TPR = topiramate, PHB = phenobarbitone, VPA = valproate, DZM = diazepam, LMG = lamotrigine.

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