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Br J Ophthalmol 84:517-522 doi:10.1136/bjo.84.5.517
  • Original Article
    • Laboratory science

T cells and fibroblasts in affected extraocular muscles in early and late thyroid associated ophthalmopathy

Table 4

Statistical analysis of mean cell counts (×400 field) of positive cells in the EOMs of early, late TAO and control specimens using the Mann-Whitney U-Wilcoxon rank sum W test

Specimens CD45RB CD45RO CD20 CD4 CD8 MAC HLA-DR
Early TAO (n=5)
 Mean rank 18.50 19.00 10.00 16.50 13.30 18.20 13.00
Normal EOM (n=16)
 Mean rank 8.66 8.50 11.31 9.28 10.28 8.75 10.38
 p Value 0.0004 0.0001 0.7190 0.0194 0.3539 0.0012 0.4451
Late TAO (n=12)
 Mean rank 19.58 19.50 15.50 17.75 14.42 18.25 17.17
Normal EOM (n=16)
 Mean rank 10.69 10.75 13.75 12.06 14.56 11.69 12.50
 p Value 0.0037 0.0044 0.59 0.0735 0.9818 0.0373 0.1457

  • n = number of samples.

  • Statistical analysis refers to comparisons between samples from TAO and normal EOM using the same Ab.

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