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Br J Ophthalmol 84:531-533 doi:10.1136/bjo.84.5.531
  • Scientific correspondence

Lupus anticoagulant positivity in insulin dependent diabetic patients: an additional risk factor in the pathogenesis of diabetic retinopathy?

Table 2

Haemocoagulative variables in diabetic patients and in healthy controls (n=mean value (SD))

LA positive (n= 10) LA negative (n = 22) Control group (n = 50) p value
LA positive v LA negative LA positive v controls LA negative v controls
Lupus anticoagulant (titre) 1.59 (0.03) 0.98 (0.001) <0.001
Activated protein C (mmol/l) 82.0 (17.3) 102.82 (19.9) 95.22 (13.7) 0.0082 0.0168 0.1064
F1+2 (mmol/l) 1.14 (0.37) 0.68 (0.42) 0.80 (0.23) 0.0146 0.0190 0.2002
Fibrinogen (g/l) 2.99 (0.47) 2.89 (0.51) 2.94 (0.46) 0.6694 0.5320 0.6248
PT (ratio) 1.10 (0.40) 1.20 (0.30) 1.10 (0.20) 0.3600 0.6125 0.2399
PTT (ratio) 1.20 (0.30) 1.30 (0.20) 1.20 (0.20) 0.0914 0.5254 0.0622

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