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Br J Ophthalmol 2000;84:667 doi:10.1136/bjo.84.6.667e
  • Letter to the Editor

The teardrop sign: a rare dermatological reaction to brimonidine

  1. JENNIFER T SCRUGGS,
  2. JULIA WHITESIDE-MICHEL,
  3. MICHAEL C BRODSKY
  1. Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
  1. Michael C Brodsky, MD, Arkansas Children's Hospital, 800 Marshall, Little Rock, AR, 72202, USA brodskymichaelc{at}exchange.uams.edu
  • Accepted 6 January 2000

Editor,—Brimonidine is a potent, highly selective α2 adrenergic agonist used for the treatment of open angle glaucoma and ocular hypertension. It lowers intraocular pressure by decreasing aqueous humour production and increasing uveoscleral outflow.1 2 The most common ocular and periocular side effects of brimonidine include ocular hyperaemia, itching, burning, or stinging; foreign body sensation, blurred vision, allergic, toxic, or follicular conjunctivitis, and lid hyperaemia.3 The following case describes a previously unreported periocular reaction to this medication.

CASE REPORT

A 23 year old white …

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