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Br J Ophthalmol 84:1045-1049 doi:10.1136/bjo.84.9.1045
  • Original Article
    • Laboratory science

Optic nerve oxygen tension: effects of intraocular pressure and dorzolamide

Table 1

Mean (SE) values of arterial blood pH, arterial carbon dioxide and oxygen tensions (Pco 2, Po2 ) and mean arterial blood pressure before and after administration of 500 mg dorzolamide intravenously

   Before dorzolamide After dorzolamide n p value
Arterial blood pH (units) 7.64  (0.05) 7.49  (0.04) 6 <0.0005
Arterial blood Pco 2 (kP) 3.4 (0.4) 5.1 (0.5) 6 <0.0005
Arterial blood Po 2(kP) 13 (1) 13 (1) 6 0.3
Mean arterial blood pressure (mm Hg) 81 (7) 84 (6) 6 0.09
  • The number of pigs (n), and the p value for the pairedt test are indicated.

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