Side effects of cyclosporin
| Case | Malaise | Cramps | Mg | Incr BP | Other | Creat incr |
Final creat (μmol/l) |
| 1 | N | N | 1.25 | N | N | N | 82 |
| 2 | N | N | NA | N | N | N | 97 |
| 3 | N | N | 0.74 | N | I | Y–2 months | 77 |
| 4 | Y | N | 0.85 | N | G, L | Y–single test | 80 |
| 5 | N | N | 0.78 | N | N | Y–1 year | 106 |
| 6 | Y | N | 0.71 | N | N | Y–2 months | 93 |
| 7 | N | N | 0.83 | N | N | N | 92 |
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Malaise = any recorded systemic symptom (tiredness, fatigue, nausea, vomiting, temperature intolerance) recorded in case notes, regardless of whether this necessitated change in treatment. Cramps = any muscle cramps recorded in case notes. Incr BP = rise in blood pressure sufficient to require change in treatment. Other = any other adverse effects recorded in case notes, regardless of whether this necessitated change in treatment: I = secondary infection (infectious keratitis), G = gingival hyperplasia, L = lymphopenia (transient in this case). Creat incr = raised level of plasma creatinine above 120 μmol/l; N = nil, Y = yes with duration specified.
