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Br J Ophthalmol 85:6-10 doi:10.1136/bjo.85.1.6
  • Original Article
    • Clinical science

Ultrastructure of the vitreoretinal interface following plasmin assisted vitrectomy

Table 1

Scanning electron microscopy of the vitreoretinal interface

Concentration and duration of exposure No of eyes Remnants of vitreous cortex
Posterior pole Equator Vitreous base
1 U plasmin, 30 minutes 5 ++ ++ +++
++ ++ +++
++ +++ +++
++ ++ +++
++ ++ +++
1 U plasmin, 60 minutes 5 + + +++
+ ++ +++
+ + +++
+ + +++
++ ++ +++
2 U plasmin, 30 minutes 5 + + +++
+ + +++
+ + +++
– + +++
+ + +++
2 U plasmin, 60 minutes 5 – + +++
– + +++
– + +++
– + +++
– + +++
Plasmin treated eyes without incubation 4 +++ +++ +++
Control fellow eyes 24 +++ +++ +++

  • +++ = No vitreoretinal separation, vitreous cortex attached to the inner limiting membrane (ILM); ++ = vitreoretinal separation but continuous network of collagen fibrils covering the ILM; + = sparse collagen fibrils covering the ILM;—= bare ILM.

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