Keratolysis in a patient with pemphigus vulgaris
- MASAHIRO SUAMI,
- MASARU KATO,
- KENRO KOIDE,
- YOSHIMASA USAMI,
- NORIMASA HATA,
- HIROYUKI MACHIDA,
- YOSHIHIRO HOTTA
- Department of Ophthalmology, Hamamatsu University, School of Medicine, Japan
- Department of Dermatology
- Department of Ophthalmology, Hamamatsu University, School of Medicine, Japan
- Department of Dermatology
- Accepted for publication 16 April 2001
Editor,—Pemphigus vulgaris is an autoimmune, blistering disease of the skin and mucous membranes.1 The characteristic ocular finding is conjunctivitis, and corneal involvement is rare.2 3 We present a case with pemphigus vulgaris with severe keratolysis that required a corneal transplantation.
CASE REPORT
A 41 year old man had suffered from pemphigus vulgaris for 2 years, and prednisolone 40 mg/day and cyclosporine 300 mg/day had been prescribed. He was admitted to the Hamamatsu University Hospital on 15 March 1999 with an acute exacerbation of the symptoms because of non-compliance with the corticosteroid therapy. He returned on 17 March 1999 because of increased discharge and visual loss in both eyes. His visual acuity was 20/20 right eye and 20/20 left eye, and his intraocular pressure was 24 mm Hg right eye and 20 mm Hg left eye. No remarkable findings were observed …
