Crystalluria with sulphadiazine
- Moorfields Eye Hospital, City Road
- London EC1V 2PD, UK
- Accepted for publication 25 April 2001
Editor,—Toxoplasmosis is the commonest cause of posterior uveitis worldwide. Ocular toxoplasmosis may occur as part of the primary acquired infection or through reactivation of encysted organisms at the edge of an old chorioretinal scar.
Current indications for treatment include sight threatening lesions at or adjacent to macula or papillomacular bundle and disc or marked vitritis.
Treatment is commonly with a combination of the synergistic antagonists of folate metabolism, sulphadiazine, and pyrimethamine. Folinic acid rescue is added to prevent bone marrow suppression. Steroids are frequently used in combination with antimicrobials in sight threatening inflammatory foci of infection.
We report a case of acute ureteric obstruction in a young female with her first presentation of recurrent ocular toxoplasmosis. We would …
