Prepared strip (Pre-S) containing 1.3 μl of 0.5% fluorescein placed into inferior fornix 5 minutes after instilling 10 μl of 0.4% benoxinate into the same eye and 5 minutes after instilling 10 μl of 0.5% fluorescein diluted in 0.4% benoxinate into the fellow eye. Schirmer's test read after 5 minutes. A TCR of 1 reflects a concentration of fluorescein of 0.5% at 5 minutes. Log TFI is the natural logarithm
| Schirmer (mm) | TCR | TFI | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre-S | Drop | Pre-S | Drop | Pre-S | Drop | ||||||
| Non-Sjögren's syndrome | |||||||||||
| Mean | 11.5 | 11.5 | 0.072 | 0.073 | 207 | 221 | |||||
| SD | 4.68 | 5.10 | 0.035 | 0.037 | 157 | 186 | |||||
| p Value | 0.52 | 0.618 | 0.19 | ||||||||
| Sjögren's syndrome | |||||||||||
| Mean | 2.29 | 2.54 | 0.438 | 0.357 | 8.61 | 10.4 | |||||
| SD | 1.66 | 1.34 | 0.298 | 0.225 | 7.97 | 7.85 | |||||
| p Value | 0.27 | 0.152 | 0.94 | ||||||||









