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Br J Ophthalmol 85:397-402 doi:10.1136/bjo.85.4.397
  • Original Article
    • Clinical science

The a-wave of the dark adapted electroretinogram in glaucomas: are photoreceptors affected?

Table 2

Comparison of the a-wave's amplitude at 10, 11, and 12 ms between the normal and the glaucoma group

Flash intensity (cd/s/m2) Normal group a-wave's amplitude (μV) (mean and (SD)) Glaucoma group a-wave's amplitude (μV) (mean and (SD)) p Value
Time at which the response magnitudes were measured (ms)
10 11 12 10 11 12 10 11 12
9.4 299 (58) 331 (61) 352 (61) 235 (87) 255 (88) 165 (67) 0.006 0.005 0.004
5.3 238 (42) 273 (47) 302 (51) 165 (67) 191 (74) 214 (79) 0.004 0.004 0.004
1.7 79 (23) 95 (27) 112 (32) 64 (28) 78 (34) 92 (40) ns ns ns
0.5 35 (12) 44 (14) 52 (17) 26 (12) 31 (14) 37 (16) ns ns ns
0.2 23 (16) 28 (18) 34 (21) 11 (6) 14 (8) 17 (9) ns ns ns
  • Comparing the normal and the glaucoma group, the a-wave's amplitude showed a significant difference for flash intensities of 5.3 and 9.4 cd/s/m2, but not for lower luminances. The table shows the mean a-wave's amplitudes with standard deviations (SD) and the results of the unpaired t test for each flash intenity and for the three fixed times of 10, 11, and 12 ms at which the response magnitudes were measured.

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