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Br J Ophthalmol 85:567-575 doi:10.1136/bjo.85.5.567
  • Original Article
    • Clinical science

Amniotic membrane transplantation for partial limbal stem cell deficiency

Table 1

Clinical characteristics of patients with partial limbal stem cell deficiency

Patient/ age/sex Eye No of previous procedures LSCD (degrees) /TAC Diagnosis Visual acuity Follow up (months) Epithelial healing (days) IC Notes
Preop Postop Change (lines)
1/30/M RE 0 300 Chemical burn 20/30 20/30 0 22 20
2/4/M LE 1 350 Radiation keratopathy HM 1/200 0 17.2 Radiation neuropathy Stromal revascularisation
3/45/M RE 2 150 Chemical burn 20/100 20/400 −3 12 30 Yes
4/35/M RE 0 270 Chemical burn 20/60 20/25 4 33 Stromal revascularisation
5/39/M LE 0 150 Chemical burn, BK/PED HM 20/40 10 37 30
6/26/M RE 0 180 Chemical burn, Symblepharon 20/300 20/25 9 32 18
7/40/F LE 0 330 Chemical burn, Dry eye 20/300 20/40 7 34 60 Yes Stromal revascularisation
8/44/F LE RE 0 300 270 CL induced keratitis CL induced keratitis 20/400 20/400 20/25 20/25 1 2 23 20.6 — — Yes
9/65/F LE 4 120 HSK, fungal keratitis, multiple surgeries LP LP 0 14 Yes Eviscerated for phthisis bulbi
10/37/F/ RE LE 0 240 240 Idiopathic Idiopathic 20/400 20/100 20/40 20/60 8 3 25 23 7 5 Stromal revascularisation
11/68/M RE 5 90 Multiple glaucoma surgeries 20/200 20/50 5 25 13
12/74/M LE 0 330 CIN 5/200 20/400 1 18 ARMD
13/28/F LE 0 300 Chemical burn 20/25 20/20 1 21
14/52/F RE 1 350 Yes Idiopathic 20/100 20/30 6 13 30 Yes Treated with CsA
15/47/M LE 0 350 Yes Chemical burn 20/25 20/20 1 14.8 15 Yes
  • ARMD = age related macular degeneration; BK = band keratopathy; CIN = conjunctival intraepithelial neoplasia; CL = contact lens; CsA = cyclosporin A; 5-FU = 5-fluorouracil; HSK = herpes simplex keratitis; IC = impression cytology; LSCD = limbal stem cell deficiency; RE = right eye; LE = left eye; PED = persistent epithelial defect; TAC = central transient amplifying cells intact; VA = visual acuity; HM = hand motion; LP = light perception; — = not recorded.

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