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Letter to the Editor
Bilateral acute retinal necrosis and herpes simplex type 2 encephalitis in a neonate
  1. ANDRÉS KYCHENTHAL
  1. Moorfields Eye Hospital, London, UK
  2. St George's Hospital, Department of Ophthalmology, London, UK
  3. Moorfields Eye Hospital, London, UK
  1. ANDREW COOMBES,
  2. JOHN GREENWOOD
  1. Moorfields Eye Hospital, London, UK
  2. St George's Hospital, Department of Ophthalmology, London, UK
  3. Moorfields Eye Hospital, London, UK
  1. CARLOS PAVESIO,
  2. GEORGE W AYLWARD
  1. Moorfields Eye Hospital, London, UK
  2. St George's Hospital, Department of Ophthalmology, London, UK
  3. Moorfields Eye Hospital, London, UK
  1. George W Aylward, Vitreoretinal Service, Moorfields Eye Hospital, London EC1V 2PD, UK

https://doi.org/10.1136/bjo.85.5.625f

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    Editor,—Acute retinal necrosis (ARN) is a rapidly progressing, sometimes devastating, retinitis associated with the herpes virus family. First described in 1971,1 it is diagnosed by the clinical triad of progressive peripheral retinal necrosis, occlusive vasculopathy, and vitreous inflammation.2 The association of herpetic encephalitis with ARN has been described in adults.34 Herpes simplex virus type 2 (HSV-2) has also been recognised as one of the causative agents of the ARN syndrome, particularly in Japan.5 It has been suggested that ARN in patients less than 25 years of age is likely to be caused by HSV-2.6 We present a case of bilateral ARN (BARN) in a neonate with HSV-2 encephalitis.

    CASE REPORT

    A 25 day old infant presented with a 4 day history of lethargy, poor feeding, and coughing. …

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