Single dose intranasal administration of retinal autoantigen generates a rapid accumulation and cell activation in draining lymph node and spleen: implications for tolerance therapy

Andrew D Dick; Vijay Sharma; Janet Liversidge

doi:10.1136/bjo.85.8.1001

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Original Article

Single dose intranasal administration of retinal autoantigen generates a rapid accumulation and cell activation in draining lymph node and spleen: implications for tolerance therapy

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Online download statistics by month: July 2001 to March 2024

	Abstract	Full	Pdf
Jul 2001	22	19	3
Aug 2001	7	26	6
Sep 2001	5	26	14
Oct 2001	2	11	5
Nov 2001	1	7	2
Dec 2001	2	11	0
Jan 2002	4	14	6
Feb 2002	2	5	0
Mar 2002	6	6	4
Apr 2002	3	10	0
May 2002	1	8	6
Jun 2002	2	10	8
Jul 2002	2	8	2
Aug 2002	2	4	2
Sep 2002	1	5	3
Oct 2002	1	9	10
Nov 2002	2	9	7
Dec 2002	1	9	8
Jan 2003	0	5	8
Feb 2003	0	3	2
Mar 2003	2	5	2
Apr 2003	0	1	2
May 2003	2	5	4
Jun 2003	3	5	8
Jul 2003	8	22	7
Aug 2003	11	19	3
Sep 2003	13	22	2
Oct 2003	9	18	1
Nov 2003	14	20	8
Dec 2003	7	18	7
Jan 2004	14	14	3
Feb 2004	4	8	4
Mar 2004	10	24	5
Apr 2004	13	36	3
May 2004	36	60	15
Jun 2004	37	51	7
Jul 2004	39	56	5
Aug 2004	24	44	9
Sep 2004	22	35	4
Oct 2004	8	23	7
Nov 2004	9	53	11
Dec 2004	8	18	5
Jan 2005	9	10	9
Feb 2005	8	36	0
Mar 2005	8	24	4
Apr 2005	5	16	12
May 2005	2	9	5
Jun 2005	8	12	8
Jul 2005	2	8	5
Aug 2005	3	11	11
Sep 2005	6	15	4
Oct 2005	4	17	3
Nov 2005	3	11	29
Dec 2005	2	8	5
Jan 2006	7	11	8
Feb 2006	1	8	4
Mar 2006	1	11	4
Apr 2006	0	14	3
May 2006	7	6	7
Jun 2006	4	5	2
Jul 2006	4	9	4
Aug 2006	0	4	4
Sep 2006	2	8	4
Oct 2006	3	14	4
Nov 2006	4	8	6
Dec 2006	0	11	2
Jan 2007	1	11	4
Feb 2007	1	14	11
Mar 2007	1	10	5
Apr 2007	10	4	2
May 2007	7	4	4
Jun 2007	9	4	2
Jul 2007	2	4	9
Aug 2007	3	1	10
Sep 2007	4	2	1
Oct 2007	7	1	1
Nov 2007	5	5	5
Dec 2007	1	5	7
Jan 2008	2	6	4
Feb 2008	5	2	5
Mar 2008	6	5	6
Apr 2008	2	3	4
May 2008	3	5	4
Jun 2008	4	6	7
Jul 2008	8	0	0
Aug 2008	35	2	1
Sep 2008	10	4	1
Oct 2008	7	2	1
Nov 2008	9	0	2
Dec 2008	11	2	5
Jan 2009	15	3	1
Feb 2009	3	1	1
Mar 2009	13	2	0
Apr 2009	27	0	1
May 2009	6	0	0
Jun 2009	5	1	0
Jul 2009	10	0	0
Sep 2009	9	1	2
Oct 2009	5	1	0
Nov 2009	3	2	1
Dec 2009	9	1	0
Jan 2010	0	1	1
Feb 2010	4	1	2
Mar 2010	4	0	0
Apr 2010	1	1	2
May 2010	9	4	3
Jun 2010	5	0	4
Jul 2010	0	1	4
Aug 2010	2	12	2
Sep 2010	5	3	2
Oct 2010	8	8	1
Nov 2010	15	1	1
Dec 2010	4	4	0
Jan 2011	8	1	1
Feb 2011	5	11	3
Mar 2011	4	4	1
Apr 2011	3	2	2
May 2011	5	5	2
Jun 2011	7	0	0
Jul 2011	5	1	1
Aug 2011	2	6	3
Sep 2011	1	0	1
Oct 2011	2	2	1
Nov 2011	2	7	2
Dec 2011	5	4	5
Jan 2012	5	3	3
Feb 2012	4	12	3
Mar 2012	8	1	6
Apr 2012	4	5	6
May 2012	2	5	5
Jun 2012	5	5	2
Jul 2012	5	10	9
Aug 2012	11	11	9
Sep 2012	3	8	6
Oct 2012	6	5	9
Nov 2012	6	8	8
Dec 2012	4	4	3
Jan 2013	7	13	3
Feb 2013	5	2	5
Mar 2013	4	6	4
Apr 2013	4	7	6
May 2013	8	6	5
Jun 2013	5	6	5
Jul 2013	4	2	2
Aug 2013	3	4	4
Sep 2013	2	5	3
Oct 2013	4	6	6
Nov 2013	10	5	4
Dec 2013	9	1	5
Jan 2014	5	3	3
Feb 2014	1	1	0
Mar 2014	4	4	1
Apr 2014	7	5	5
May 2014	3	7	8
Jun 2014	2	6	1
Jul 2014	4	7	3
Aug 2014	2	11	17
Sep 2014	4	3	6
Oct 2014	3	8	5
Nov 2014	0	4	11
Dec 2014	4	0	3
Jan 2015	0	3	5
Feb 2015	2	4	11
Mar 2015	16	9	5
Apr 2015	1	3	1
May 2015	1	9	14
Jun 2015	0	4	10
Jul 2015	4	13	1
Aug 2015	3	7	13
Sep 2015	9	3	5
Oct 2015	1	3	1
Nov 2015	5	4	8
Dec 2015	0	2	8
Jan 2016	3	4	8
Feb 2016	0	0	1
Mar 2016	3	2	0
Apr 2016	2	5	2
May 2016	7	6	8
Jun 2016	1	4	4
Jul 2016	4	7	9
Aug 2016	2	3	2
Sep 2016	7	2	4
Oct 2016	4	3	6
Nov 2016	10	5	6
Dec 2016	9	6	3
Jan 2017	8	2	0
Feb 2017	2	1	1
Mar 2017	2	5	4
Apr 2017	0	7	3
May 2017	0	10	0
Jun 2017	0	5	4
Jul 2017	13	12	5
Aug 2017	8	8	2
Sep 2017	52	52	1
Oct 2017	126	126	3
Nov 2017	77	77	0
Dec 2017	66	66	2
Jan 2018	28	28	4
Feb 2018	23	23	0
Mar 2018	14	14	0
Apr 2018	15	15	0
May 2018	19	20	0
Jun 2018	19	19	1
Jul 2018	22	20	0
Aug 2018	15	15	0
Sep 2018	36	36	1
Oct 2018	20	20	0
Nov 2018	19	19	2
Dec 2018	16	16	4
Jan 2019	22	18	2
Feb 2019	16	12	3
Mar 2019	2	2	4
Apr 2019	6	6	6
May 2019	13	9	5
Jun 2019	20	16	8
Jul 2019	24	16	6
Aug 2019	27	19	4
Sep 2019	17	13	4
Oct 2019	15	14	2
Nov 2019	15	13	4
Dec 2019	13	11	3
Jan 2020	12	10	3
Feb 2020	13	11	4
Mar 2020	14	10	2
Apr 2020	16	16	3
May 2020	15	15	2
Jun 2020	14	14	5
Jul 2020	25	25	2
Aug 2020	8	8	3
Sep 2020	15	15	1
Oct 2020	12	12	3
Nov 2020	6	6	2
Dec 2020	27	18	3
Jan 2021	10	6	4
Feb 2021	2	1	3
Mar 2021	8	8	1
Apr 2021	5	5	3
May 2021	6	6	3
Jun 2021	2	2	6
Jul 2021	6	6	8
Aug 2021	0	0	3
Sep 2021	4	4	7
Oct 2021	5	5	15
Nov 2021	2	2	13
Dec 2021	4	4	1
Jan 2022	6	6	4
Feb 2022	6	7	4
Mar 2022	10	8	5
Apr 2022	8	8	2
May 2022	17	17	14
Jun 2022	20	19	8
Jul 2022	11	11	2
Aug 2022	25	25	4
Sep 2022	18	17	15
Oct 2022	26	27	4
Nov 2022	7	7	4
Dec 2022	7	5	2
Jan 2023	1	1	2
Feb 2023	10	9	2
Mar 2023	1	1	1
Apr 2023	1	1	1
May 2023	5	5	7
Jun 2023	2	2	0
Jul 2023	6	6	5
Aug 2023	4	4	9
Sep 2023	4	2	3
Oct 2023	8	8	1
Nov 2023	7	7	1
Dec 2023	13	0	0
Jan 2024	14	0	0
Feb 2024	9	1	1
Mar 2024	14	0	0
Total	2358	2729	1124

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