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Br J Ophthalmol 85:1007 doi:10.1136/bjo.85.8.1007c
  • Letter to the Editor

The tubulointerstitial nephritis and uveitis (TINU) syndrome is associated with HLA-DR14 in Spanish patients

Table 1

Main clinical manifestations of the patients. Their HLA phenotype is also shown

Case 1 Case 2 Case 3
Sex Female Female Female
Age 69 51 49
First symptoms Nausea and anorexia Upper respiratory infection Asymptomatic, coincidental finding
Uveitis Bilateral AAU Bilateral AAU with papillitis Bilateral AAU with retinal vasculitis
Onset of uveitis 4 months after the nephritis Unknown, at the time or possibly prior to the nephitis 5 months after the nephritis
HLA phenotype A24, A32, B62, B39, Bw6, Cw7, Cw3, DR14, DR8, DR52, DQ5 A28, B57, Bw4, DR11, DR14, DR52, DQ5 A3, A24, B35, B7, Bw6, Cw4, DR103, DR3, DR52, DQ5
  • AAU = acute anterior uveitis.

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