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Br J Ophthalmol 85:925-927 doi:10.1136/bjo.85.8.925
  • Scientific correspondence

Is the pulse rate useful in assessing risk of diabetic retinopathy and macular oedema? The Wisconsin Epidemiological Study of Diabetic Retinopathy

Table 2

Multivariate logistic regression models of any retinopathy, progression, progression to proliferative retinopathy, and incidence of macular oedema

Incidence of any retinopathy Progression of retinopathy Progression to proliferative retinopathy Incidence of macular oedema
OR (95% CI) p Value OR (95% CI) p Value OR (95% CI) p Value OR (95% CI) p Value
Younger onset:
 Pulse rate, 10 bpm 1.00 (0.82, 1.22) 0.98 0.94 (0.83, 1.07) 0.3 1.01 (0.8, 1.28) 0.95 1.09 (0.88, 1.35) 0.44
 Duration (years) 1.17 (1.07, 1.29) 0.001
 Glycosylated Hb (%) 1.53 (1.29, 1.81) 0.0001 1.63 (1.48, 1.8) 0.0001 1.75 (1.49, 2.05) 0.0001 1.37 (1.2, 1.56) 0.0001
 Systolic BP (mm Hg) 1.04 (1.02, 1.07) 0.0008
 Diastolic BP (mm Hg) 1.02 (1.00, 1.04) 0.01
 Retinopathy at baseline, step 1.67 (1.49, 1.87) 0.0001 1.24 (1.16, 1.34) 0.0001
Older onset:
 Pulse rate, 10 bpm 1.07 (0.9, 1.26) 0.43 1.07 (0.95, 1.22) 0.27 1.11 (0.81, 1.5) 0.52 1.07 (0.8, 1.44) 0.65
 Age (years) 0.97 (0.96, 0.99) 0.01 0.96 (0.95, 0.98) 0.0001 0.95 (0.91, 0.99) 0.02
 Glycosylated Hb (%) 1.34 (1.18, 1.52) 0.0001 1.39 (1.27, 1.52) 0.0001 1.34 (1.09, 1.65) 0.006 1.49 (1.24, 1.79) 0.0001
 Duration (years) 1.03 (1.00, 1.05) 0.03
 Retinopathy at baseline, step 1.64 (1.44, 1.87) 0.0001 1.28 (1.17, 1.41) 0.0001
  • Glycosylated Hb = Glycosylated haemoglobin; bpm = beats per minute.

  • OR = odds ratio. The OR shown is that associated with each indicated increment in the independent variable.

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