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Br J Ophthalmol 85:1065-1069 doi:10.1136/bjo.85.9.1065
  • Original Article
    • Clinical science

Failure of amniotic membrane transplantation in the treatment of acute ocular burns

Table 1

Demographics and clinical data

Patient No Sex/age Agent/eye Key findings Non-ocular injuries Days between injury and AMT Additional procedures Indication for additional procedures Outcome
1 Male/45 Thermal/L Lid burns, 95% conjunctival loss, 360° limbal ischaemia, 100%ED with stromal clouding, no iris details, 2° glaucoma nil 13 Lateral tarsorrhaphy
Vitreous biopsy
Upper lid reconstruction Tectonic PK
Rpt AMT
Lat tarsorrhaphy
Buccal mucous memb graft to lids
Corneal exposure
To exclude endophthalmitis
Lid necrosis
Corneal perforation Persistent epithelial defect Corneal exposure
Poor lid closure
Lid sparing exenteration
8 months after injury
2a Male/65 Alkali/R Lid burns, fixed globe, 100% conjunctival loss, 360° limbal ischaemia,100%ED with melting cornea, flat AC, cataract Burns of face, left shoulder and back 8 Rpt AMT
Lamellar limbal corneal graft with AMT
UL reconstruction
Aspiration of lens matter
Persistent epithelial defect Corneal melt


UL symblepharon
Swollen cataract
Autoevisceration 1 year after injury
2b Male/65 Alkali/L Lid burns, fixed globe, 100% conjunctival loss, 360º limbal ischaemia,100%ED with melting cornea, flat AC, cataract Burns of face, left shoulder and back 8 Rpt AMT Persistent epithelial defect Autoevisceration 50 days after injury
3 Male/40 Acid/R Lid burns, 100% conjunctival loss, 360° limbal ischaemia, 100% ED with stromal clouding, cataract Burns of scalp and shoulders 19 Tenoplasty
Keratolimbal allograft and AMT Living related limbal allograft
LL symblepharon correction Keratolimbal allograft and AMT Tarsorrhaphy and entropion surgery
Lamellar patch corneal graft Large tectonic PK Keratoprosthesis with vitrectomy, RD surgery silicone oil and replacement of graft
Limbal ischaemia
Persistent epithelial defect Persistent epithelial defect Symblepharon and exposure Persistent epithelial defect Entropion and corneal exposure
Corneal perforation
Corneal perforation
Retinal detachment
Phthysis bulbi 2 years after injury
  • ED = epithelial defect; AC = anterior chamber; PK = penetrating keratoplasty; AMT = amniotic membrane transplantation; UL = upper lid; LL = lower lid; RD = retinal detachment.

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