Table 3
Changes in glucose, lactate, and pH of eight different test media following 21 days of human corneal organ culture at 31°C
| Test medium |
Δ [glucose] (mM) |
Δ [lactate] (mM) |
Glycolysis
(%) |
Δ pH(units) |
| MEM-8% | −4.9 (0.4) | 8.5 (0.2) | 85 (5) | −0.64 (0.14)e |
| MEM-2% | −4.5 (0.2) | 7.2 (0.4) | 81 (6) | −0.39 (0.10)f |
| MEM-G | −5.0 (0.3) | 7.9 (0.2) | 78 (4) | −0.51 (0.05)g |
| F99 | −4.3 (0.6) | 7.5 (0.4) | 88 (9) | −0.64 (0.07)h |
| F99-Sr | −5.5 (1.4) | 7.8 (1.4) | 72 (11) | −0.67 (0.05)i |
| M199 | −4.8 (0.5) | 7.5 (1.0) | 78 (10) | −0.37 (0.06)j |
| SFM | −7.3 (1.9)a | 12.4 (2.0)c | 85 (10) | −0.65 (0.17)k |
| DIF-1000 | −6.9 (1.9)b | 6.9 (0.6) | 54 (11)d | −0.39 (0.07)l |
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Data are mean (SD), n=9.
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Δ = day 21–day 0.
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↵assuming an equivalence of one mol glucose to two mol lactate and ignoring other metabolic pathways.
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One way analysis of variance and Student-Newman-Keuls method for all pairwise comparisons (within each column) revealed the following significant differences (p<0.05): (a versus all except b); (b versus all except a); (c versus all); (d versus all); (e, h, i, k versus f, g, j, l); (g versus f, j, l).
