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Br J Ophthalmol 85:1110-1114 doi:10.1136/bjo.85.9.1110
  • Original Article
    • Laboratory science

Pentoxifylline influences the autocrine function of organ cultured donor corneas and enhances endothelial cell survival

Table 2

Donor age, postmortem time, and mean concentration of donor derived endotoxin detected within the media bathing 17 (I–XVII) fellow pairs (right eye and left eye) of cultured donor corneas during the initial 10 day phase of incubation

Corneal pair no Donor age (years) Postmortem time (hours) Endotoxin (units/ml)
Initial 1–10 day phase of organ culture
RE LE
I 24 21 0.685 (+) 0.715 (+)
II 33 21 0.89 (+) 0.982 (+)
III 41 16 0.429 (−) 0.595 (−)
IV 30 18 0.720 (+) 0.685 (+)
V 23 2 0.637 (+) 0.732 (+)
VI 16 17 >1.0 (+) >1.0 (+)
VII 48 1 0.697 (+) 0.543 (−)
VIII 45 21 0.435 (−) 0.482 (−)
IX 56 2 0.453 (−) 0.548 (−)
X 53 17 0.494 (−) 0.518 (−)
XI 58 19 >1.0 (+) >1.0 (+)
XII 67 5 >1.0 (+) 0.298 (−)
XIII 41 44 0.476 (−) 0.596 (−)
XIV 48 24 0.857 (+) 0.655 (+)
XV 72 18 0.554 (−) 0.685 (+)
XVI 48 24 0.959 (+) 0.720 (+)
XVII 40 26 0.595 (−) 0.631 (+)
  • Media were considered to register negative for endotoxin (−) if the level fell below 0.600 units/ml and to be endotoxin positive (+) if it exceeded this value.

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