Dense Kayser-Fleischer ring in asymptomatic Wilson's disease (hepatolenticular degeneration)
- 1Department of Ophthalmology, Birmingham and Midlands Eye Hospital, City Hospital, Western Road, Birmingham B18 7QU, UK
- 2Department of Ophthalmology, East Surrey Hospital, Surrey, UK
- 3Department of Ophthalmology, Wolverhampton Eye Infirmary, Wolverhampton, West Midlands, UK
- Correspondence to: Miss C A Sullivan, Birmingham and Midlands Eye Hospital, City Hospital, Western Road, Birmingham B18 7QU, UK
- Accepted 6 June 2001
The Kayser-Fleischer ring is the single most important diagnostic sign in Wilson's disease; it is found in 95% of patients. Virtually all patients with Kayser-Fleischer rings have neurological manifestations.1 Pseudo rings have been described in other conditions.1 The density of a Kayser-Fleischer ring correlates with the severity of Wilson's disease.2 We describe a rare case of a dense Kayser-Fleischer ring in an asymptomatic patient with an extremely high liver copper content. The recent significant genetic advances, and the clinical implications are discussed.
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