Table 2
Patient data
| No | Age/sex | Diagnosis | Indication | Treatment | TG | FU | Post-treatment result | Complications |
|---|---|---|---|---|---|---|---|---|
| PAM, primary acquired melanosis; PED, persistent epithelial defect; g MMC mitomycin C 0.04% eye drops; CA, carcinoma; TG, treatment group; FU, follow up in months. | ||||||||
| 1 | 61/F | Conj melanoma + PAM + atypia | 18 May 98 | A | 23 | Adequate clearance | Nil | |
| Excision + MMC | Extending just to margins | |||||||
| 0.4 mg/ml × 3 mins | No recurrence | |||||||
| 2 | 61/F | RE Conj melanoma × 6/12 | Recurrence | 26 Nov 98 | A | 17 | Regression despite margins | Nil |
| Margins not clear | Excision + MMC | NOT clear | ||||||
| 0.4 mg/ml × 4 mins | ||||||||
| 3 | 72/M | RE Bulbar conj | Margins not clear. | 05 Aug 99 | A | 8 | Clear margins on specimens | Nil |
| Bowenoid dysplasia | Risk of recurrence | Excision + MMC | No recurrence | |||||
| 0.4 mg/mi × 3 mins + conj autograft | ||||||||
| 4 | 41/F | PAM with mild atypia | Increasing in size | 23 Mar 00 | A | 1 | Good response | Nil |
| Excision + MMC | ||||||||
| 0.4 mg/ml × 3.5 min | ||||||||
| 5 | 71/F | Conj CA in situ | Recurrence + 2° cicatricial change | g MMC | B | Aborted after 4 days + PED | ||
| 6 | 89/F | LE Conj melanoma | Margins not clear | Mar 96 proton beam therapy | B | Good response | ||
| Extensive lesions | ||||||||
| Post-proton residual pig | Jun 99 | Poorly tolerated | ||||||
| g MMC | ||||||||
| 7 | 57/M | LE Conj PAM + atypia | Extensive lesions | Dec 98 + | B | 16 | Regression | Nil |
| Jun 99 | ||||||||
| g MMC | Cryo to residual pigment | |||||||
| 8 | 73/F | RE Conj PAM + atypia | Recurrence of melanoma + margins not clear | Jul 99 | B | 9 | Regression | Nil |
| g MMC | ||||||||
| 9 | 64/F | Conj squamous CA | Canalicular involvement | 06 Jan 00 g MMC | C | 3 | Reduction in size | Reaction in the second phase but continued with topical steroid cover |
| 06 Apr 00 | 1 | Good response | ||||||
| Excision + MMC | Retaining VA 6/6 | |||||||
| 0.4 mg/ml × 3.5 mins | ||||||||
| 10 | 65/F | Sebaceous gland CA | Extensive lesions + caruncle involved | 21 Jan 00 | C | 4 | Some reduction in size | Nil |
| g MMC | ||||||||
| 27 Apr 00 | ||||||||
| Excision | ||||||||
| 11 | 80/F | Sebaceous gland CA | Intra-epithelial spread | 02 Jul 98 | D | 18 | PED | |
| Excision + MMC | ||||||||
| 0.4 mg/ml × 3 mins + | ||||||||
| g MMC × 2/52 | ||||||||
| 06 Jan 00 | 4 | Biopsy | PED | |||||
| Recurrence | g MMC × 3/52 | −ve on 13.06.00 | ||||||
