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Br J Ophthalmol 86:1089-1092 doi:10.1136/bjo.86.10.1089
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Pulsatile ocular blood flow: the effect of the Valsalva manoeuvre in open angle and normal tension glaucoma: a case report and prospective study

Table 3

Effect of Valsalva on heart rate, IOP, and POBF

Normal NTG POAG p Value
NS = non-significant at 5% level.
Note: refer to text for explanation of “adjusted” p values.
Mean Valsalva heart rate (SD), (bpm) (n=60) 82.3 (15.4) 71.6 (10.8) 82.9 (14.2) 0.025
Mean change in heart rate (SD), (bpm) (n=60) 10.3 (11.6) 6.6 (7.1) 11.3 (9.6) NS
Mean Valsalva IOP (SD), (mm Hg) (n=61) 18.1 (4.0) 16.5 (5.1) 22.7 (5.6) 0.001
Mean change in IOP (SD) (mm Hg) (n=61) +2.1 (2.4) +0.9 (2.5) −0.6 (1.8) 0.002
Mean Valsalva POBF (SD) (μl/min) (n=58) 773.4 (221.9) 739.7 (328.1) 537.8 (512.1) NS
Mean fall in POBF (SD), (μl/min) (n=58) 375.0 (311.0) 221.0 (259.5) 334.7 (374.4) NS (0.294 unadjusted 0.542 adjusted)

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