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Br J Ophthalmol 2002;86:1319-1320 doi:10.1136/bjo.86.11.1319-b
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Anti-Acanthamoeba efficacy in contact lens disinfecting systems

  1. T K Beattie1,
  2. A Tomlinson1,
  3. D V Seal2
  1. 1Department of Vision Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, UK
  2. 2Applied Vision Research Centre, City University, Northampton Square, London EC1V 0HB, UK
  1. Correspondence to: Tara Beattie; t.k.beattie{at}gcal.ac.uk

    Hiti et al1 produced an interesting study investigating the susceptibility of three strains of Acanthamoeba to a PHMB (polyhexamethylene biguanide) based multipurpose solution (MPS), a one step peroxide system (3% H2O2), and a two step peroxide system (0.6% H2O2). However, no comment was made regarding the choice of strains tested, only one of which (A castellanii 4CL) was typical of those that cause keratitis in humans. This isolate belongs to genotype T4, the predominant genotype in Acanthamoeba keratitis.2,3 Their second strain (A hatchetti 11DS) is of T6 genotype, which, with the exception of one incident,4 has not previously been reported as causing keratitis. The third strain (A lenticulata 72/2) belongs to genotype T5,2,3 and as the authors themselves state “has not been reported to cause Acanthamoeba keratitis.” Although testing of all three strains was of interest to the microbiologist, the …

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