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Br J Ophthalmol 86:1428-1433 doi:10.1136/bjo.86.12.1428
  • Original Article
    • Laboratory science

TGFβ-Smad signalling in postoperative human lens epithelial cells

Table 1

Summary of the cases and the results

Presence/absence of nuclear Smads3/4 positive cells
Epithelial-type cells adjacent to regenerated lens fibres in Sommerring’s ring Cells amid fibrous matrix accumulation
Case No Age* Sex Duration Cause† Smad3 Smad4 Smad3 Smad4
*Age at the removal of the intraocular lens (IOL); † duration between implantation and explantation of the IOL; y = year(s); ‡CCC = continuous circular capsulorhexis; PVR = IOL removal to obtain the better observation of the fundus during vitrectomy for proliferative vitreoretinopathy; capsulotomy = obtained by anterior capsulotomy during cataract surgery; − = negative; + = positive (regardless the incidence of positive cells); NE = not examined.
1 65 F CCC‡
2 72 M CCC
3 58 M CCC
4 72 F Lens dislocation
5 28 M 6 days IOL dislocation + + NE NE
6 64 M 10 days PVR + + NE NE
7 58 F 14 days PVR + + NE NE
8 68 F 0.65 y PVR + + + +
9 75 F 0.75 y PVR + + + +
10 51 M 1 y Malignant glaucoma + + + +
11 53 M 3 y PVR + + NE NE
12 75 M 2.7 y IOL dislocation + + + +
13 78 M 4 y PVR + + + +
14 80 M 4 y PVR + + + +
15 76 M 4.6 y IOL dislocation + + + +
16 68 M 5 y IOL dislocation + + + +
17 77 F 5.4 y PVR + + + +
18 77 F 6.2 y IOL dislocation + +
19 60 M 8 y IOL dislocation NE NE
20 68 M 9 y IOL dislocation + + NE NE
21 31 M 10 y IOL dislocation

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