Viability of Acanthamoeba after exposure to a multipurpose disinfecting contact lens solution and two hydrogen peroxide systems
- 1Department of Ophthalmology, University of Graz, Austria
- 2Department of Medical Parasitology, Clinical Institute of Hygiene, University of Vienna, Austria
- Correspondence to: Professor H Aspöck, Department of Medical Parasitology, Clinical Institute of Hygiene, University of Vienna, Kinderspitalgasse 15, 1095 Vienna, Austria; Horst.Aspoeck{at}univie.ac.at
- Accepted 30 August 2001
Abstract
Background/aim: Contact lens cases contaminated with Acanthamoeba are a major risk factor for an infection of the eye. In this study the anti-Acanthamoeba activity of three different contact lens storage solutions was tested.
Methods: A new multipurpose contact lens storage solution (Meni Care Plus) and a two step (Titmus H2O2) and one step (Oxysept Comfort) hydrogen peroxide system were tested for their effects on trophozoites and cysts of three different Acanthamoeba species: A castellanii, A hatchetti, and A lenticulata.
Results: After a soaking time of 8 hours (overnight soaking of contact lenses) the Titmus H2O2 0.6% solution showed very good amoebicidal effects, while Oxysept Comfort 3% H2O2 could not effectively destroy the cysts of any of the three tested species. Viable cysts of the species A lenticulata and A hatchetti were still present after exposure to Meni Care Plus (0.0005% PHMB) for 8 hours.
Conclusion: Not all of the three tested contact lens storage solutions have sufficient amoebicidal effects. The two step peroxide system Titmus H2O2 is a very effective disinfectant contact lens solution in order to avoid a possible Acanthamoeba infection of the eye.
