“It was mama also, a year later, who hustled him off to Kansas City for expensive eyeglasses. Though he had been badly handicapped by poor eyesight a long time—“blind as a mole,” in his words—no one seems to have noticed until the night of July 4th fireworks when Matt saw him responding more to the sound of the skyrockets than to the spectacle overhead. The Kansas City optometrist diagnosed a rare malformation called “flat eyeballs” (hypermetropia, which means the boy was farsighted) and Matt agreed to a pair of double strength wire rimmed spectacles. (

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Malignant hyperthermia is a disorder of skeletal muscle that may present as a life threatening hypermetabolic process in susceptible patients exposed to inhalation anaesthetics and depolarising muscle relaxants. Mutations in the gene that involve skeletal muscle rayanobine receptor (RYR1) are considered a common cause of this disorder. A recent report from the University of Health Sciences in Washington DC demonstrates that the frequency and distribution of RYR1 mutations in the North American population were markedly different from those previously identified in Europe. Although more than 20 RYR1 mutations have been identified further studies are necessary to clarify the type and frequency of mutations associated with malignant hyperthermia in different populations. (

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Candida albicans is …