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Br J Ophthalmol 86:381-386 doi:10.1136/bjo.86.4.381
  • Scientific correspondence

Pathology of cyclodiode laser: a series of nine enucleated eyes

Table 1

Clinical features and histopathology of globes with diode laser cyclophotocoagulation

Case Age/ sex Cause of glaucoma Type of treatment Time of treatment prior to enucleation Clinical response* Pars plicata injury Pars plana injury Other complications Phthisis Reason for enucleation
*Clinical response is measured as IOP (mm Hg); †15002 = 1500 mW × 1500 ms. CRVO = central retinal vein occlusion, PXF = pseudoexfoliation, PK = penetrating keratoplasty, PCIOL = posterior chamber intraocular lens, COAG = chronic open angle glaucoma, MM = malignant melanoma, Trab = trabeculectomy, ACIOL = anterior chamber intraocular lens.
1 F/80 Neovascular (CRVO) Diode 360° 40 × 1500 ms × 1500 mW 8 months IOP 78→22 Late rise →48 Moderate Not affected No Perforated microbial keratitis; high IOP
2 F/64 Absolute PXF Diode 360° 40 × 1500 ms × 1500 mW 5 months IOP 44→19 IOP 34 @ 4 weeks IOP 50 @ 6 weeks IOP 40 @ 4 weeks Moderate to severe Severe No Blind, painful, high IOP
3 F/64 Epithelial downgrowth post PK ×2; sutured PCIOL Diode 180° 4–10 o'clock: 23 burns × 1500 ms × 1500 mW 12 months IOP 56→10 Rise to 22–30 @ 4 months Severe Mild No Recurrent high IOP, rapidly enlarging cystic bleb
4 M/65 Chronic angle closure glaucoma after penetrating keratoplasty. Diode ×3 #1 270° 12–9 o'clock, 30 × 15002 † #2 180° 10–4 o'clock, 20 × 15002; #3 180° 3–9 o'clock, 2000 mW × 1500 ms 2 years 1 month 1 year 7 months 11 months #1 no IOP change; #2 IOP 50→18, but PK failed, IOP→ 28 #3 IOP→17 Severe Severe Scleral damage No Painful, with unresolved inferior herpes simplex virus keratitis (IOP controlled)
5 M/71 R COAG Diode 270° 3–12 o'clock 2200 mW × 18 shots 7 months IOP 48→50 @ 3 and 4 months Moderate to severe Moderate Necrosis of iris base, apposed to angle No High IOP Total hyphaema,-blood stained cornea
6 M/44 Neovascular Diode 270° 12–9 o'clock, 2000 ms × 1700–2000 mW 4 months IOP 42→20; IOP increased again to 48 @ 4 months Moderate Not affected Iris base necrosis Scleral damage No Blind, painful, total retinal detachment
7 M/74 Neovascular post plaque for choroidal MM; failed L trab. Diode 180° 10–4 o'clock; 20 × 15002 4 years 1 month IOP response poor; 40+ at enucleation Mild Not affected No Recurrent inflammation?active tumour, blind painful eye
8 F/31 Neovascular, tractional retinal detachment (surgery including silicone oil), chronic uveitis Diode × 4 #1 inf 180° 22 × 15002 #2 lat 180° 20 × 15002 #3 3–12 o/clock 1510mW × 2100 ms #4 360° 1750–2000 ms × 1500–2000 mW #1 6 months #2 4 months #3 6 weeks #4 2 weeks #1 26→21 #2 45→38→16 #3 38→11→40 #4 40→21→14 Moderate to severe Mild Iris necrosis; Scleral damage No Persisting pain despite IOP control
9 M/75 R traumatic aphakia; epithelial downgrowth post 2° ACIOL Diode ×2 #1 Inf 180° 2000 mW × 1500 ms; #2 Nasal 180° 20002 #1 7 months>br>#2 5 months IOP 42→16, but 35 @ 6 weeks; #2 Rx →IOP 14, 16 Moderate to severe Mild No Persisting pain due to corneal decompensation despite IOP control

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