Clinical features and histopathology of globes with diode laser cyclophotocoagulation
| Case | Age/ sex | Cause of glaucoma | Type of treatment | Time of treatment prior to enucleation | Clinical response* | Pars plicata injury | Pars plana injury | Other complications | Phthisis | Reason for enucleation | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| *Clinical response is measured as IOP (mm Hg); †15002 = 1500 mW × 1500 ms. | CRVO = central retinal vein occlusion, PXF = pseudoexfoliation, PK = penetrating keratoplasty, PCIOL = posterior chamber intraocular lens, COAG = chronic open angle glaucoma, MM = malignant melanoma, Trab = trabeculectomy, ACIOL = anterior chamber intraocular lens. | ||||||||||||||||||||
| 1 | F/80 | Neovascular (CRVO) | Diode 360° 40 × 1500 ms × 1500 mW | 8 months | IOP 78→22 Late rise →48 | Moderate | Not affected | – | No | Perforated microbial keratitis; high IOP | |||||||||||
| 2 | F/64 | Absolute PXF | Diode 360° 40 × 1500 ms × 1500 mW | 5 months | IOP 44→19 IOP 34 @ 4 weeks IOP 50 @ 6 weeks IOP 40 @ 4 weeks | Moderate to severe | Severe | – | No | Blind, painful, high IOP | |||||||||||
| 3 | F/64 | Epithelial downgrowth post PK ×2; sutured PCIOL | Diode 180° 4–10 o'clock: 23 burns × 1500 ms × 1500 mW | 12 months | IOP 56→10 Rise to 22–30 @ 4 months | Severe | Mild | – | No | Recurrent high IOP, rapidly enlarging cystic bleb | |||||||||||
| 4 | M/65 | Chronic angle closure glaucoma after penetrating keratoplasty. | Diode ×3 #1 270° 12–9 o'clock, 30 × 15002 † #2 180° 10–4 o'clock, 20 × 15002; #3 180° 3–9 o'clock, 2000 mW × 1500 ms | 2 years 1 month 1 year 7 months 11 months | #1 no IOP change; #2 IOP 50→18, but PK failed, IOP→ 28 #3 IOP→17 | Severe | Severe | Scleral damage | No | Painful, with unresolved inferior herpes simplex virus keratitis (IOP controlled) | |||||||||||
| 5 | M/71 | R COAG | Diode 270° 3–12 o'clock 2200 mW × 18 shots | 7 months | IOP 48→50 @ 3 and 4 months | Moderate to severe | Moderate | Necrosis of iris base, apposed to angle | No | High IOP Total hyphaema,-blood stained cornea | |||||||||||
| 6 | M/44 | Neovascular | Diode 270° 12–9 o'clock, 2000 ms × 1700–2000 mW | 4 months | IOP 42→20; IOP increased again to 48 @ 4 months | Moderate | Not affected | Iris base necrosis Scleral damage | No | Blind, painful, total retinal detachment | |||||||||||
| 7 | M/74 | Neovascular post plaque for choroidal MM; failed L trab. | Diode 180° 10–4 o'clock; 20 × 15002 | 4 years 1 month | IOP response poor; 40+ at enucleation | Mild | Not affected | – | No | Recurrent inflammation?active tumour, blind painful eye | |||||||||||
| 8 | F/31 | Neovascular, tractional retinal detachment (surgery including silicone oil), chronic uveitis | Diode × 4 #1 inf 180° 22 × 15002 #2 lat 180° 20 × 15002 #3 3–12 o/clock 1510mW × 2100 ms #4 360° 1750–2000 ms × 1500–2000 mW | #1 6 months #2 4 months #3 6 weeks #4 2 weeks | #1 26→21 #2 45→38→16 #3 38→11→40 #4 40→21→14 | Moderate to severe | Mild | Iris necrosis; Scleral damage | No | Persisting pain despite IOP control | |||||||||||
| 9 | M/75 | R traumatic aphakia; epithelial downgrowth post 2° ACIOL | Diode ×2 #1 Inf 180° 2000 mW × 1500 ms; #2 Nasal 180° 20002 | #1 7 months>br>#2 5 months | IOP 42→16, but 35 @ 6 weeks; #2 Rx →IOP 14, 16 | Moderate to severe | Mild | – | No | Persisting pain due to corneal decompensation despite IOP control | |||||||||||









