Frequency of symptoms and signs at visit 1 and visit 2 in P-DP group
| Visit 1 (preserved) | Visit 2 (preservative free) | ||||
|---|---|---|---|---|---|
| No* | (%) | No* | (%) | p Value | |
| *Number of patients for which the variable had been recorded. | |||||
| Patient symptoms | |||||
| Discomfort upon instillation | 28/57 | 50.9% | 8/56 | 14.3% | <0.001 |
| Patients presenting with at least one symptom between instillations | 48/57 | 84.2% | 31/57 | 54.4% | <0.001 |
| Ocular signs found at the clinical examination (patients presenting with at least one) | |||||
| Palpebral signs | 25/57 | 43.9% | 7/57 | 12.3% | <0.001 |
| Conjunctival signs | 44/56 | 78.6% | 25/57 | 43.9% | <0.001 |
| Superficial punctate keratitis | 13/57 | 22.8% | 5/56 | 8.9% | <0.001 |









