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Br J Ophthalmol 86:418-423 doi:10.1136/bjo.86.4.418
  • Clinical science

Prevalence of ocular symptoms and signs with preserved and preservative free glaucoma medication

Table 5

Frequency of symptoms and signs at visit 1 and visit 2 in P-DP group

Visit 1 (preserved) Visit 2 (preservative free)
No* (%) No* (%) p Value
*Number of patients for which the variable had been recorded.
Patient symptoms
    Discomfort upon instillation 28/57 50.9% 8/56 14.3% <0.001
    Patients presenting with at least one symptom between instillations 48/57 84.2% 31/57 54.4% <0.001
Ocular signs found at the clinical examination (patients presenting with at least one)
    Palpebral signs 25/57 43.9% 7/57 12.3% <0.001
    Conjunctival signs 44/56 78.6% 25/57 43.9% <0.001
    Superficial punctate keratitis 13/57 22.8% 5/56 8.9% <0.001

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