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Br J Ophthalmol 87:28-31 doi:10.1136/bjo.87.1.28
  • Scientific correspondence

A multicentre randomised double masked clinical trial of a new formulation of topical cysteamine for the treatment of corneal cystine crystals in cystinosis

Table 2

Efficacy study at 1 year: corneal cystine crystal score (CCCS) changes from baseline

Standard formulation New formulation
*p=0.04.
≥1 unit improvement* 7 (47%) 1 (7%)
<1 unit improvement 4 (27%) 2 (13%)
No change 3 (20%) 7 (47%)
<1 unit worsening 1 (7%) 5 (33%)
≥1 unit worsening 0 (0%) 0 (0%)
Total 15 15

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