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Br J Ophthalmol 87:1363-1369 doi:10.1136/bjo.87.11.1363
  • Clinical science
    • Extended reports

The effect of simulated obstructive apnoea on intraocular pressure and pulsatile ocular blood flow in healthy young adults

Table 3

Effect of Mueller manoeuvres (−20 cm H2O and −40 cm H2O) on POBF relative to baseline measurements

Subject Mueller manoeuvre −20 cm H2O Mueller manoeuvre −40 cm H2O
Inspiratory effort Change in POBF relative to baseline Inspiratory effort Change in POBF relative to baseline
Duration (seconds) Mean P (cm H2O) M2A (% (SD)) M2B (% (SD)) p value Duration (seconds) Mean P (cm H2O) M4A (% (SD)) M4B (% (SD)) p value
Analyses include repeated ANOVA and Student-Newman Keuls post hoc tests for each subject separately, and for the group as a whole. Only significant p values are shown.
*Group mean (SEM).
†p⩽0.05 relative to baseline.
‡p⩽0.01 relative to baseline.
§p⩽0.05 relative to early Mueller manoeuvre.
1 28.4 −25.4 −14.7 (13.5) −10.1 (7.7) 27.4 −45.8 7.8 (18.1) 19.7 (11.3)
2 14.6 −15.0 17.6 (10.4)† 13.0 (18.7) 0.045 29.8 −38.1 31.4 (6.2)‡ 49.4 (7.5)‡§ <0.001
3 15.0 −15.8 12.0 (8.2)† 14.2 (13.0)† 0.008 22.9 −34.8 28.9 (8.4)‡ 26.4 (7.6)‡ <0.001
4 15.8 −15.3 20.2 (10.2)‡ 12.2 (10.9)†§ <0.001 31.0 −44.7 29.8 (5.1)‡ 20.4 (8.2)‡§ <0.001
5 41.9 −21.6 7.4 (15.9) 32.8 (69.8) 21.4 −37.3 −15.5 (8.2)‡ −8.1 (8.5)§ <0.001
6 32.4 −20.5 −0.7 (6.1) 5.6 (11.3) 25.1 −41.7 −15.2 (6.4)‡ 11.1 (9.9)§ <0.001
7 42.7 −22.6 45.2 (36.5)† 79.2 (42.5)† 0.014 44.0 −41.5 −6.7 (9.5) 17.6 (15.2)§ 0.028
All 27.3 −19.5 12.4 (7.1)* 21.0 (10.8)* 27.4 −40.6 8.6 (8.1)* 19.5 (6.5)*† 0.039

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